Victor Ortiz-Soriano 1 ,Katherine Donaldson 2 ,Gaixin Du 3 ,Ye Li 4 ,Joshua Lambert 5 ,Dan Cleland 6 ,Alice Thornton 7 ,Laura C Fanucchi 8 ,Moises A Huaman 9 10 ,Javier A Neyra 11
Đang xem: gaixin du
Affiliations
1 Division of Nephrology, Bone and Mineral Metabolism, Department of Internal Medicine, University of Kentucky Medical Center, Lexington, KY 40506, USA. vor223
uky.edu. 2 Division of Nephrology, Bone and Mineral Metabolism, Department of Internal Medicine, University of Kentucky Medical Center, Lexington, KY 40506, USA. katherine.donaldson
uky.edu. 3 Center for Health Services Research, University of Kentucky, Lexington, KY 40506, USA. gaixin.du
ucmail.uc.edu. 6 Center for Health Services Research, University of Kentucky, Lexington, KY 40506, USA. dan.cleland
uky.edu. 7 Division of Infectious Diseases, Department of Internal Medicine, University of Kentucky Medical Center, Lexington, KY 40506, USA. alice.thornton
uky.edu. 8 Division of Infectious Diseases, Department of Internal Medicine, University of Kentucky Medical Center, Lexington, KY 40506, USA. laura.fanucchi
uky.edu. 9 Division of Infectious Diseases, Department of Internal Medicine, University of Kentucky Medical Center, Lexington, KY 40506, USA. huamanms
ucmail.uc.edu. 10 Division of Infectious Diseases, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH 45221, USA. huamanms
ucmail.uc.edu. 11 Division of Nephrology, Bone and Mineral Metabolism, Department of Internal Medicine, University of Kentucky Medical Center, Lexington, KY 40506, USA. javier.neyra
Victor Ortiz-Soriano 1 ,Katherine Donaldson 2 ,Gaixin Du 3 ,Ye Li 4 ,Joshua Lambert 5 ,Dan Cleland 6 ,Alice Thornton 7 ,Laura C Fanucchi 8 ,Moises A Huaman 9 10 ,Javier A Neyra 11
Xem thêm: Nghĩa Của Từ Overlooking Là Gì, Nghĩa Của Từ Overlook, Khác Biệt Giữa Oversee Và Overlook
Affiliations
1 Division of Nephrology, Bone and Mineral Metabolism, Department of Internal Medicine, University of Kentucky Medical Center, Lexington, KY 40506, USA. vor223
uky.edu. 2 Division of Nephrology, Bone and Mineral Metabolism, Department of Internal Medicine, University of Kentucky Medical Center, Lexington, KY 40506, USA. katherine.donaldson
uky.edu. 3 Center for Health Services Research, University of Kentucky, Lexington, KY 40506, USA. gaixin.du
ucmail.uc.edu. 6 Center for Health Services Research, University of Kentucky, Lexington, KY 40506, USA. dan.cleland
uky.edu. 7 Division of Infectious Diseases, Department of Internal Medicine, University of Kentucky Medical Center, Lexington, KY 40506, USA. alice.thornton
uky.edu. 8 Division of Infectious Diseases, Department of Internal Medicine, University of Kentucky Medical Center, Lexington, KY 40506, USA. laura.fanucchi
uky.edu. 9 Division of Infectious Diseases, Department of Internal Medicine, University of Kentucky Medical Center, Lexington, KY 40506, USA. huamanms
ucmail.uc.edu. 10 Division of Infectious Diseases, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH 45221, USA. huamanms
ucmail.uc.edu. 11 Division of Nephrology, Bone and Mineral Metabolism, Department of Internal Medicine, University of Kentucky Medical Center, Lexington, KY 40506, USA. javier.neyra
Xem thêm: Nghĩa Của Từ Fitting Là Gì, Fitting Là Gì Fitting, Có Thể
Acute kidney injury (AKI) is a frequent complication of hospitalized patients with infective endocarditis (IE). Further, AKI in the setting of IE is associated with high morbidity and mortality. We aimed to examine the incidence, clinical parameters, and hospital costs associated with AKI in hospitalized patients with IE in an endemic area with an increasing prevalence of opioid use. This retrospective cohort study included 269 patients admitted to a major referral center in Kentucky with a primary diagnosis of IE from January 2013 to December 2015. Of these, 178 (66.2%) patients had AKI by Kidney Disease Improving Global Outcomes (KDIGO) serum creatinine criteria: 74 (41.6%) had AKI stage 1 and 104 (58.4%) had AKI stage ≥2. In multivariable analysis, higher comorbidity scores and the need for diuretics were independently associated with AKI, while the involvement of the tricuspid valve and the need for vasopressor/inotrope support were independently associated with severe AKI (stage ≥2). The median total direct cost of hospitalization was progressively higher according to each stage of AKI ($17,069 for no AKI; $37,111 for AKI stage 1; and $61,357 for AKI stage ≥2; p
